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4-Dinitrochlorobenzene
4-Dinitrochlorobenzene
4-dinitrochlorobenzene is a chemical compound that is used in laboratory settings.4-dinitrochlorobenzene It has a unique structure that features a chlorine atom substituted into the benzene ring with two nitro groups located at the 2 and 4 positions on the molecule. This unique molecular design has made it an important research tool for scientists investigating electrophilic aromatic substitution reactions and immunological mechanisms.
Like other chemicals that have the potential to interact with the immune system, 4-dinitrochlorobenzene may be able to cause adverse side effects in some individuals.4-dinitrochlorobenzene These side effects include skin irritation, itching, and swelling. In some cases, these symptoms can become severe enough to lead to blistering or ulceration of the skin. Due to its ability to induce delayed-type hypersensitivity (DTH) responses in humans, 4-dinitrochlorobenzene should only be used in carefully controlled experiments and by highly trained scientists.
SKIN SENSITIVITY
The DTH sensitizing property of 4-dinitrochlorobenzene makes it an important substance to study the interaction of electrophilic aromatic substitution reactions with the immune system.4-dinitrochlorobenzene DTH reactions are the result of the interaction of molecules with lipids found in cells and tissues. In order to test these interactions, scientists utilize chemical compounds known as DTH reagents. 4-dinitrochlorobenzene, also known as DNCB, is one of these DTH reagents that has been extensively studied in laboratories around the world.
Human Toxicity Excerpts (Complete)
Based on its Koc value of 501 and its water solubility, 1-chloro-2,4-dinitrobenzene is not expected to be mobile in soil.4-dinitrochlorobenzene It is also known that nitrobenzenes adsorb strongly to clay particles and their mobility is therefore expected to be low in sediments with high clay content(SRC).
In inhalation tests, 1-chloro-2,4-dinitrobenzene was found to have no toxicity in mice at 10 ppb over 6 weeks of exposure(1).4-dinitrochlorobenzene It has also been shown that 1-chloro-2,4-dinitrobenzene does not significantly adsorb to the common mineral montmorillonite clay(SRC).
Ecotoxicity Excerpts (Complete)
In the soil leachate test, 1
1-chloro-2,4-dinitrobenzene absorbs UV light strongly at 290 nm and is susceptible to photochemical degradation in the environment. It is likely that the formation of hydroxyl radicals plays an important role in its photodegradation in natural waters(SRC).
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